The prevalence and risk factors of group B streptococcus colonization in Iranian pregnant women
نویسندگان
چکیده
BACKGROUND Group B Streptococcus (GBS) is a leading cause of serious neonatal infections. Although great progress has been made in preventing prenatal GBS, its colonization rate in different regions of Iran remains unknown. AIM To determine GBS colonization prevalence and its risk factors among Iranian pregnant women. METHODS This prospective cross-sectional study was performed on 186 pregnant women, who attended Boo-Ali hospital which is affiliated with Islamic Azad University in Tehran, Iran, from March 2014 to June 2015. The demographic, obstetric and gynecological data were gathered. A recto-vaginal culture was taken from each patient, with a sterile swab, in lithotomy position without using speculum, and vaginal pH was measured. Patients with positive GBS received IV antibiotic therapy during labor (penicillin G 3 gram at first dose then 1.5 gram Q/4h until delivery). Data were analyzed by statistical software SPSS version 21. Statistical tests for differences were performed by Chi-square test. Potential confounding was assessed by logistic regression. Level of significance was set at p<0.05. RESULTS Twenty-two (11.8%) patients had positive recto-vaginal colonization. No significant differences between colonized and GBS-negative women with regard to age, obstetrics history and socio-economic factor were noticed. In contrast, smoking, history of previous infection with HPV, presence of vulvitis and a vaginal pH>4.5 were associated with GBS colonization (p≤0.05). CONCLUSIONS With a relatively low prevalence and few significantly correlated factors, it is hardly possible to define a high risk group of pregnant women for GBS colonization. Therefore, thorough measures should be taken in order to prevent infection complications in mothers and neonates in the Iranian population.
منابع مشابه
The Prevalence of Group B Streptococcus Colonization in Iranian Pregnant Women and Its Subsequent Outcome
متن کامل
A survey on the prevalence of group B Streptococcus in pregnant women referred to the obstetrics and Gynecology ward at babol Ayatollah Rouhani hospital
OBJECTIVES:Prenatal infections are one of the fundamental causes of early puerperal complications in mothers and neonates. These infections are mostly due to colonized organisms in pregnant woman's genitor-urinary system. The aim of this study was to determine the incidence of streptococcus group B (GBS) colonization in parturient women and the rate of pathogen transmission to the newborn. METH...
متن کاملEpidemiologic Pattern of Vaginal Colonization by Group B Streptococcus in Pregnant Women in Hamadan, Central West of Iran
Group B Streptococcus (GBS) is a leading cause of serious neonatal infections. Although great progress has been made in preventing prenatal GBS, its colonization rate in different regions ofIran remains unknown. The objective of this study was to determine the colonization rate of GBS in pregnant women in Hamadan city, Central west of Iran. A group of 544 pregnant women were randomly selected a...
متن کاملFrequency of Group B Streptococcal Colonization in Pregnant Women Aged 35-37 Weeks in Clinical Centers of Shahed University, Tehran, Iran
Background & Objectives: One of the important infectious factors in pregnant mothers and newborns is Group B Streptococcus (GBS). There is no perfect report about prevalence of GBS in Iran and in the case of preterm rupture of amniotic membrane or preterm labor all patients are treated by antibiotics without culture so this has led to adverse taking antibiotics and drug resistance. The...
متن کاملPrevalence of positive recto-vaginal culture for Group B streptococcus in pregnant women at 35-37 weeks of gestation
Background: Recto-vaginal colonization of Group B streptococcus (GBS) has been known as an important issue in mother and newborn’s health, which is getting frequent in developing countries. Screening test have been introduced and utilized in many countries and is recommended by many researchers. However, due to lack of information in prevalence of GBS, especially in Iran, there are doubts and ...
متن کاملComparative Molecular and Microbiologic Diagnosis of Vaginal Colonization by Group B Streptococcus in Pregnant Women during Labor
Objective(s) Rapid tests for detection of Streptococcus agalactiae or Group B Streptococci (GBS) at the onset of labor are needed to permit early intrapartum antibiotic prophylaxis. This study aimed to evaluate the PCR assays targeting the 16S ribosomal RNA gene (16S rDNA) for detection of the GBS in comparison with a specific culture method. Materials and Methods Two swabs were used to obta...
متن کامل